Drug interactions
Diazoxide + Telmisartan-amlodipine
Severity: Moderate
Diazoxide and Telmisartan-amlodipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Diazoxide is a vasodilator that lowers blood pressure and can raise blood glucose. Used with telmisartan-amlodipine, it may cause excessive hypotension.
What this interaction means in plain words
Diazoxide and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Diazoxide belongs to Miscellaneous; Telmisartan-amlodipine belongs to Cardiovascular.
Why it happens
Additive vasodilatory and antihypertensive effects, as diazoxide opens potassium channels in vascular smooth muscle.
What to do
Monitor blood pressure closely, particularly at initiation or dose changes, and reduce antihypertensive doses if hypotension occurs. Monitor glucose in diabetic patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telmisartan-amlodipine
- Aliskiren + Telmisartan-amlodipine Contraindicated
- Sparsentan + Telmisartan-amlodipine Contraindicated
- Amifostine + Telmisartan-amlodipine Major
- Amiloride + Telmisartan-amlodipine Major
- Benazepril + Telmisartan-amlodipine Major
- Candesartan + Telmisartan-amlodipine Major
Other interactions of Diazoxide
Frequently asked questions
Can I take Diazoxide with Telmisartan-amlodipine?
MediHelp rates the interaction as moderate. Diazoxide and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Diazoxide is a vasodilator that lowers blood pressure and can raise blood glucose. Used with telmisartan-amlodipine, it may cause excessive hypotension.
How serious is the interaction between Diazoxide and Telmisartan-amlodipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure closely, particularly at initiation or dose changes, and reduce antihypertensive doses if hypotension occurs. Monitor glucose in diabetic patients.
What other medicines interact with Telmisartan-amlodipine?
MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.
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