Drug interactions
Dichlorphenamide + Formoterol-mometasone
Severity: Moderate
Dichlorphenamide and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dichlorphenamide, a carbonic anhydrase inhibitor, causes potassium loss and metabolic acidosis, and formoterol can further lower serum potassium. Combined use may produce additive hypokalemia with arrhythmia risk.
What this interaction means in plain words
Dichlorphenamide and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dichlorphenamide belongs to Miscellaneous; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive hypokalemia from renal potassium wasting (carbonic anhydrase inhibition) and beta-2 mediated intracellular potassium shift.
What to do
Monitor serum potassium and bicarbonate periodically and replace potassium as needed. Take extra care in patients with cardiac disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Dichlorphenamide
Frequently asked questions
Can I take Dichlorphenamide with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Dichlorphenamide and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dichlorphenamide, a carbonic anhydrase inhibitor, causes potassium loss and metabolic acidosis, and formoterol can further lower serum potassium. Combined use may produce additive hypokalemia with arrhythmia risk.
How serious is the interaction between Dichlorphenamide and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and bicarbonate periodically and replace potassium as needed. Take extra care in patients with cardiac disease.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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