Drug interactions
Diclofenac + Ginger
Severity: Minor
Diclofenac and Ginger: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginger may have mild antiplatelet activity, which could add to the bleeding tendency caused by diclofenac. Clinical evidence is weak and the effect is likely small at dietary amounts.
What this interaction means in plain words
Diclofenac and Ginger have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Diclofenac belongs to Musculoskeletal; Ginger belongs to Gastrointestinal Tract.
Why it happens
Possible additive antiplatelet effect through inhibition of thromboxane synthesis by ginger constituents.
What to do
Advise patients to report unusual bruising or bleeding. High-dose ginger supplements should be used cautiously with long-term diclofenac.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Diclofenac
- Diclofenac + Ketorolac Contraindicated
- Diclofenac + Ketorolac intranasal Contraindicated
- Aceclofenac + Diclofenac Major
- Acemetacin + Diclofenac Major
- Alteplase + Diclofenac Major
- Amiloride + Diclofenac Major
Other interactions of Ginger
- Aceclofenac + Ginger Moderate
- Acemetacin + Ginger Moderate
- Aescin + Ginger Moderate
- Aspirin / citric acid / sodium bicarbonate + Ginger Moderate
- Aspirin rectal + Ginger Moderate
- Aspirin + Ginger Moderate
Frequently asked questions
Can I take Diclofenac with Ginger?
MediHelp rates the interaction as minor. Diclofenac and Ginger have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ginger may have mild antiplatelet activity, which could add to the bleeding tendency caused by diclofenac. Clinical evidence is weak and the effect is likely small at dietary amounts.
How serious is the interaction between Diclofenac and Ginger?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report unusual bruising or bleeding. High-dose ginger supplements should be used cautiously with long-term diclofenac.
What other medicines interact with Diclofenac?
MediHelp also lists interactions of Diclofenac with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Diclofenac page.
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