Drug interactions
Diclofenac + Ginkgo biloba
Severity: Moderate
Diclofenac and Ginkgo biloba: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginkgo may inhibit platelet-activating factor and has been linked to case reports of bleeding. With diclofenac, bleeding risk could increase.
What this interaction means in plain words
Diclofenac and Ginkgo biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive antiplatelet effect via platelet-activating factor antagonism plus NSAID cyclooxygenase inhibition.
What to do
Advise avoiding ginkgo with diclofenac where possible and monitor for bruising or bleeding if used.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Diclofenac
- Diclofenac + Ketorolac Contraindicated
- Diclofenac + Ketorolac intranasal Contraindicated
- Aceclofenac + Diclofenac Major
- Acemetacin + Diclofenac Major
- Alteplase + Diclofenac Major
- Amiloride + Diclofenac Major
Frequently asked questions
Can I take Diclofenac with Ginkgo biloba?
MediHelp rates the interaction as moderate. Diclofenac and Ginkgo biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo may inhibit platelet-activating factor and has been linked to case reports of bleeding. With diclofenac, bleeding risk could increase.
How serious is the interaction between Diclofenac and Ginkgo biloba?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding ginkgo with diclofenac where possible and monitor for bruising or bleeding if used.
What other medicines interact with Diclofenac?
MediHelp also lists interactions of Diclofenac with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Diclofenac page.
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