Drug interactions
Diclofenac + Ginko biloba
Severity: Moderate
Diclofenac and Ginko biloba: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginkgo may inhibit platelet activating factor and diclofenac impairs platelet function and can injure the gastric mucosa. Together they may increase the risk of bleeding.
What this interaction means in plain words
Diclofenac and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Diclofenac belongs to Musculoskeletal; Ginko biloba belongs to Gastrointestinal Tract.
Why it happens
Additive antiplatelet effects, with NSAID-induced mucosal injury.
What to do
Advise avoiding ginkgo with regular diclofenac and report bleeding or black stools.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ginko biloba
- Ginko biloba + Ketorolac Major
- Abciximab + Ginko biloba Moderate
- Aceclofenac + Ginko biloba Moderate
- Acemetacin + Ginko biloba Moderate
- Alteplase + Ginko biloba Moderate
- Anagrelide + Ginko biloba Moderate
Other interactions of Diclofenac
- Diclofenac + Ketorolac Contraindicated
- Diclofenac + Ketorolac intranasal Contraindicated
- Aceclofenac + Diclofenac Major
- Acemetacin + Diclofenac Major
- Alteplase + Diclofenac Major
- Amiloride + Diclofenac Major
Frequently asked questions
Can I take Diclofenac with Ginko biloba?
MediHelp rates the interaction as moderate. Diclofenac and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo may inhibit platelet activating factor and diclofenac impairs platelet function and can injure the gastric mucosa. Together they may increase the risk of bleeding.
How serious is the interaction between Diclofenac and Ginko biloba?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding ginkgo with regular diclofenac and report bleeding or black stools.
What other medicines interact with Ginko biloba?
MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.
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