Drug interactions
Diclofenac + Saw palmetto
Severity: Minor
Diclofenac and Saw palmetto: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Saw palmetto has been associated with isolated reports of bleeding and may theoretically add to NSAID bleeding risk. The evidence is weak.
What this interaction means in plain words
Diclofenac and Saw palmetto have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Diclofenac belongs to Musculoskeletal; Saw palmetto belongs to Gastrointestinal Tract.
Why it happens
Possible mild antiplatelet effect of saw palmetto; mechanism not firmly established.
What to do
Ask patients about herbal use and monitor for unusual bruising or bleeding; stop saw palmetto before surgery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Diclofenac
- Diclofenac + Ketorolac Contraindicated
- Diclofenac + Ketorolac intranasal Contraindicated
- Aceclofenac + Diclofenac Major
- Acemetacin + Diclofenac Major
- Alteplase + Diclofenac Major
- Amiloride + Diclofenac Major
Other interactions of Saw palmetto
- Aspirin rectal + Saw palmetto Moderate
- Aspirin + Saw palmetto Moderate
- Dabigatran + Saw palmetto Moderate
- Desirudin + Saw palmetto Moderate
- Ketorolac + Saw palmetto Moderate
- Meclofenamate + Saw palmetto Moderate
Frequently asked questions
Can I take Diclofenac with Saw palmetto?
MediHelp rates the interaction as minor. Diclofenac and Saw palmetto have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Saw palmetto has been associated with isolated reports of bleeding and may theoretically add to NSAID bleeding risk. The evidence is weak.
How serious is the interaction between Diclofenac and Saw palmetto?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and monitor for unusual bruising or bleeding; stop saw palmetto before surgery.
What other medicines interact with Diclofenac?
MediHelp also lists interactions of Diclofenac with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Diclofenac page.
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