Drug interactions
Diethylpropion + Oxytocin
Severity: Moderate
Diethylpropion and Oxytocin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Diethylpropion is a sympathomimetic anorectic that can raise blood pressure and heart rate, and oxytocin has its own hemodynamic effects. Combined use may cause unpredictable blood pressure changes around labor.
What this interaction means in plain words
Diethylpropion and Oxytocin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive or opposing hemodynamic effects; no established pharmacokinetic mechanism.
What to do
Monitor blood pressure and heart rate during oxytocin administration in patients taking diethylpropion. Consider holding the anorectic peripartum.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Oxytocin
- Carboprost tromethamine + Oxytocin Major
- Dinoprostone + Oxytocin Major
- Ephedrine + Oxytocin Major
- Fexinidazole + Oxytocin Major
- Givinostat + Oxytocin Major
- Misoprostol + Oxytocin Major
Frequently asked questions
Can I take Diethylpropion with Oxytocin?
MediHelp rates the interaction as moderate. Diethylpropion and Oxytocin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Diethylpropion is a sympathomimetic anorectic that can raise blood pressure and heart rate, and oxytocin has its own hemodynamic effects. Combined use may cause unpredictable blood pressure changes around labor.
How serious is the interaction between Diethylpropion and Oxytocin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate during oxytocin administration in patients taking diethylpropion. Consider holding the anorectic peripartum.
What other medicines interact with Oxytocin?
MediHelp also lists interactions of Oxytocin with, for example, Carboprost tromethamine, Dinoprostone, Ephedrine. The full list is on the Oxytocin page.
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