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Drug interactions

Diflunisal + Forskolin

Severity: Minor

Diflunisal and Forskolin: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Forskolin raises cyclic AMP and has demonstrated platelet-inhibiting activity, so it could theoretically add to NSAID bleeding risk. Clinical evidence is lacking.

What this interaction means in plain words

Diflunisal and Forskolin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Theoretical additive antiplatelet effect via cyclic AMP elevation in platelets.

What to do

Advise patients to report unusual bruising or bleeding and consider avoiding the supplement if other bleeding risks exist.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Diflunisal with Forskolin?

MediHelp rates the interaction as minor. Diflunisal and Forskolin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Forskolin raises cyclic AMP and has demonstrated platelet-inhibiting activity, so it could theoretically add to NSAID bleeding risk. Clinical evidence is lacking.

How serious is the interaction between Diflunisal and Forskolin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report unusual bruising or bleeding and consider avoiding the supplement if other bleeding risks exist.

What other medicines interact with Diflunisal?

MediHelp also lists interactions of Diflunisal with, for example, Ketorolac, Ketorolac intranasal, Acemetacin. The full list is on the Diflunisal page.

Full monographs, dosing and an interaction checker in the MediHelp app

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