Drug interactions
Diflunisal + Rose hips
Severity: Minor
Diflunisal and Rose hips: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rose hips contain vitamin C, which can acidify urine slightly and compete for renal handling of acidic drugs. Any effect on diflunisal levels is expected to be small and of doubtful clinical significance.
What this interaction means in plain words
Diflunisal and Rose hips have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible competition for renal tubular secretion and minor urinary pH changes altering salicylate excretion.
What to do
No specific action is needed; monitor for NSAID adverse effects if large quantities of rose hip products are taken.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Diflunisal
- Diflunisal + Ketorolac Contraindicated
- Diflunisal + Ketorolac intranasal Contraindicated
- Acemetacin + Diflunisal Major
- Acetazolamide + Diflunisal Major
- Alteplase + Diflunisal Major
- Amiloride + Diflunisal Major
Frequently asked questions
Can I take Diflunisal with Rose hips?
MediHelp rates the interaction as minor. Diflunisal and Rose hips have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rose hips contain vitamin C, which can acidify urine slightly and compete for renal handling of acidic drugs. Any effect on diflunisal levels is expected to be small and of doubtful clinical significance.
How serious is the interaction between Diflunisal and Rose hips?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed; monitor for NSAID adverse effects if large quantities of rose hip products are taken.
What other medicines interact with Diflunisal?
MediHelp also lists interactions of Diflunisal with, for example, Ketorolac, Ketorolac intranasal, Acemetacin. The full list is on the Diflunisal page.
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