Drug interactions
Dipyridamole + Fish oil
Severity: Minor
Dipyridamole and Fish oil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Omega-3 fatty acids have mild antiplatelet effects and could slightly add to dipyridamole's inhibition of platelet function. Clinically significant bleeding is uncommon at usual supplement doses.
What this interaction means in plain words
Dipyridamole and Fish oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dipyridamole belongs to Cardiovascular; Fish oil belongs to Gastrointestinal Tract.
Why it happens
Possible additive antiplatelet effects from omega-3-mediated changes in platelet eicosanoid synthesis.
What to do
No dose change is usually needed; monitor for bruising or bleeding, especially with high-dose fish oil.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Other interactions of Fish oil
- Antithrombin alfa + Fish oil Moderate
- Antithrombin iii + Fish oil Moderate
- Aspirin / citric acid / sodium bicarbonate + Fish oil Moderate
- Aspirin + Fish oil Moderate
- Betrixaban + Fish oil Moderate
- Bivalirudin + Fish oil Moderate
Frequently asked questions
Can I take Dipyridamole with Fish oil?
MediHelp rates the interaction as minor. Dipyridamole and Fish oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Omega-3 fatty acids have mild antiplatelet effects and could slightly add to dipyridamole's inhibition of platelet function. Clinically significant bleeding is uncommon at usual supplement doses.
How serious is the interaction between Dipyridamole and Fish oil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; monitor for bruising or bleeding, especially with high-dose fish oil.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.
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