Drug interactions
Dipyridamole + Timolol
Severity: Minor
Dipyridamole and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dipyridamole raises adenosine levels, which can slow heart rate and AV conduction. Combined with a beta-blocker, bradycardia is possible, although clinically significant episodes are uncommon.
What this interaction means in plain words
Dipyridamole and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dipyridamole belongs to Cardiovascular; Timolol belongs to Cardiovascular.
Why it happens
Additive negative chronotropic and dromotropic effects from increased adenosine and beta-blockade.
What to do
Monitor heart rate in patients with conduction disease or other bradycardic drugs. No routine dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
- Atenolol-chlorthalidone + Timolol Major
Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Frequently asked questions
Can I take Dipyridamole with Timolol?
MediHelp rates the interaction as minor. Dipyridamole and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dipyridamole raises adenosine levels, which can slow heart rate and AV conduction. Combined with a beta-blocker, bradycardia is possible, although clinically significant episodes are uncommon.
How serious is the interaction between Dipyridamole and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate in patients with conduction disease or other bradycardic drugs. No routine dose change is needed.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Timolol page.
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