Drug interactions
Dobutamine + Pseudoephedrine
Severity: Moderate
Dobutamine and Pseudoephedrine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pseudoephedrine adds adrenergic stimulation to dobutamine, which may cause excessive tachycardia, hypertension and arrhythmia. Dobutamine is used in monitored settings, which limits practical risk.
What this interaction means in plain words
Dobutamine and Pseudoephedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dobutamine belongs to Cardiovascular; Pseudoephedrine belongs to Respiratory.
Why it happens
Additive adrenergic receptor stimulation.
What to do
Avoid giving pseudoephedrine to patients receiving dobutamine; titrate dobutamine to hemodynamic response with continuous monitoring.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Pseudoephedrine
- Isocarboxazid + Pseudoephedrine Contraindicated
- Phenelzine + Pseudoephedrine Contraindicated
- Pseudoephedrine + Rasagiline Contraindicated
- Pseudoephedrine + Selegiline Contraindicated
- Pseudoephedrine + Selegiline transdermal Contraindicated
- Pseudoephedrine + Tranylcypromine Contraindicated
Other interactions of Dobutamine
Frequently asked questions
Can I take Dobutamine with Pseudoephedrine?
MediHelp rates the interaction as moderate. Dobutamine and Pseudoephedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pseudoephedrine adds adrenergic stimulation to dobutamine, which may cause excessive tachycardia, hypertension and arrhythmia. Dobutamine is used in monitored settings, which limits practical risk.
How serious is the interaction between Dobutamine and Pseudoephedrine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving pseudoephedrine to patients receiving dobutamine; titrate dobutamine to hemodynamic response with continuous monitoring.
What other medicines interact with Pseudoephedrine?
MediHelp also lists interactions of Pseudoephedrine with, for example, Isocarboxazid, Phenelzine, Rasagiline. The full list is on the Pseudoephedrine page.
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