Drug interactions
Dong quai + Etodolac
Severity: Moderate
Dong quai and Etodolac: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dong quai contains coumarin-type compounds and has been linked to increased bleeding, so with an NSAID there may be added bleeding risk. Evidence is limited to case reports and theory.
What this interaction means in plain words
Dong quai and Etodolac can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive effects on coagulation or platelet function from coumarin constituents plus NSAID platelet inhibition.
What to do
Advise patients to avoid dong quai while using etodolac, and monitor for bruising or bleeding if used.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Etodolac
- Etodolac + Ketorolac Contraindicated
- Etodolac + Ketorolac intranasal Contraindicated
- Aceclofenac + Etodolac Major
- Acemetacin + Etodolac Major
- Acetylsalicylic acid + Etodolac Major
- Alteplase + Etodolac Major
Frequently asked questions
Can I take Dong quai with Etodolac?
MediHelp rates the interaction as moderate. Dong quai and Etodolac can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dong quai contains coumarin-type compounds and has been linked to increased bleeding, so with an NSAID there may be added bleeding risk. Evidence is limited to case reports and theory.
How serious is the interaction between Dong quai and Etodolac?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid dong quai while using etodolac, and monitor for bruising or bleeding if used.
What other medicines interact with Etodolac?
MediHelp also lists interactions of Etodolac with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Etodolac page.
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