Drug interactions
Dong quai + Oxaprozin
Severity: Moderate
Dong quai and Oxaprozin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dong quai contains coumarin-type compounds and has been linked to increased INR and bleeding in case reports. It may add to the bleeding tendency of an NSAID.
What this interaction means in plain words
Dong quai and Oxaprozin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Coumarin constituents may have anticoagulant and antiplatelet effects that add to platelet inhibition by oxaprozin.
What to do
Advise avoiding dong quai while taking oxaprozin, or monitor for bruising and bleeding if it is continued.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Oxaprozin
- Ketorolac intranasal + Oxaprozin Contraindicated
- Ketorolac + Oxaprozin Contraindicated
- Aceclofenac + Oxaprozin Major
- Acemetacin + Oxaprozin Major
- Acetylsalicylic acid + Oxaprozin Major
- Alteplase + Oxaprozin Major
Frequently asked questions
Can I take Dong quai with Oxaprozin?
MediHelp rates the interaction as moderate. Dong quai and Oxaprozin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dong quai contains coumarin-type compounds and has been linked to increased INR and bleeding in case reports. It may add to the bleeding tendency of an NSAID.
How serious is the interaction between Dong quai and Oxaprozin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding dong quai while taking oxaprozin, or monitor for bruising and bleeding if it is continued.
What other medicines interact with Oxaprozin?
MediHelp also lists interactions of Oxaprozin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Oxaprozin page.
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