Drug interactions
Drospirenone + Quinine
Severity: Minor
Drospirenone and Quinine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Drospirenone is not a clinically meaningful CYP3A4 inhibitor, so a significant rise in quinine levels is not expected.
What this interaction means in plain words
Drospirenone and Quinine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Drospirenone belongs to Endocrine; Quinine belongs to Anti Parasitic.
Why it happens
Theoretical weak CYP3A4 inhibition by drospirenone; not established clinically.
What to do
No specific action is needed beyond standard quinine monitoring.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Other interactions of Drospirenone
Frequently asked questions
Can I take Drospirenone with Quinine?
MediHelp rates the interaction as minor. Drospirenone and Quinine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Drospirenone is not a clinically meaningful CYP3A4 inhibitor, so a significant rise in quinine levels is not expected.
How serious is the interaction between Drospirenone and Quinine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed beyond standard quinine monitoring.
What other medicines interact with Quinine?
MediHelp also lists interactions of Quinine with, for example, Arsenic trioxide, Dofetilide, Dronedarone. The full list is on the Quinine page.
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