Drug interactions
Echinacea + Procarbazine
Severity: Minor
Echinacea and Procarbazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Echinacea has immune-stimulating properties that could theoretically counteract the immunosuppressive and cytotoxic action of procarbazine. Clinical data in patients are lacking, so the significance is uncertain.
What this interaction means in plain words
Echinacea and Procarbazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Echinacea belongs to Gastrointestinal Tract; Procarbazine belongs to Oncology.
Why it happens
Theoretical pharmacodynamic opposition from echinacea immunostimulation; not established clinically.
What to do
Advise patients receiving procarbazine to avoid echinacea supplements. Review herbal use at oncology visits.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Echinacea
- Alefacept + Echinacea Moderate
- Antithymocyte globulin equine + Echinacea Moderate
- Antithymocyte globulin rabbit + Echinacea Moderate
- Azathioprine + Echinacea Moderate
- Basiliximab + Echinacea Moderate
- Cyclosporine + Echinacea Moderate
Other interactions of Procarbazine
- Adenovirus types 4 and 7 live + Procarbazine Contraindicated
- Amitriptyline + Procarbazine Contraindicated
- Amoxapine + Procarbazine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Bcg vaccine live + Procarbazine Contraindicated
- Brimonidine + Procarbazine Contraindicated
Frequently asked questions
Can I take Echinacea with Procarbazine?
MediHelp rates the interaction as minor. Echinacea and Procarbazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Echinacea has immune-stimulating properties that could theoretically counteract the immunosuppressive and cytotoxic action of procarbazine. Clinical data in patients are lacking, so the significance is uncertain.
How serious is the interaction between Echinacea and Procarbazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients receiving procarbazine to avoid echinacea supplements. Review herbal use at oncology visits.
What other medicines interact with Echinacea?
MediHelp also lists interactions of Echinacea with, for example, Alefacept, Antithymocyte globulin equine, Antithymocyte globulin rabbit. The full list is on the Echinacea page.
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