Drug interactions
Elderberry + Tolbutamide
Severity: Minor
Elderberry and Tolbutamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Elderberry preparations showed glucose-lowering activity in laboratory studies. With tolbutamide this could theoretically add to the hypoglycemic effect, but clinical data in humans are lacking.
What this interaction means in plain words
Elderberry and Tolbutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive blood glucose lowering based on preclinical data; not confirmed in humans.
What to do
Monitor blood glucose if elderberry products are used regularly alongside tolbutamide and watch for hypoglycemia symptoms.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolbutamide
- Glyburide-metformin + Tolbutamide Major
- Insulin degludec-liraglutide + Tolbutamide Major
- Aceclofenac + Tolbutamide Moderate
- Acemetacin + Tolbutamide Moderate
- Acetylsalicylic acid + Tolbutamide Moderate
- Albiglutide + Tolbutamide Moderate
Frequently asked questions
Can I take Elderberry with Tolbutamide?
MediHelp rates the interaction as minor. Elderberry and Tolbutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elderberry preparations showed glucose-lowering activity in laboratory studies. With tolbutamide this could theoretically add to the hypoglycemic effect, but clinical data in humans are lacking.
How serious is the interaction between Elderberry and Tolbutamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose if elderberry products are used regularly alongside tolbutamide and watch for hypoglycemia symptoms.
What other medicines interact with Tolbutamide?
MediHelp also lists interactions of Tolbutamide with, for example, Glyburide-metformin, Insulin degludec-liraglutide, Aceclofenac. The full list is on the Tolbutamide page.
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