Drug interactions
Eltrombopag + Iron dextran complex
Severity: Minor
Eltrombopag and Iron dextran complex: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iron dextran is generally given parenterally, so little chelation of oral eltrombopag is expected. An interaction would only be plausible with oral iron products.
What this interaction means in plain words
Eltrombopag and Iron dextran complex have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Chelation occurs only with cations in the gut lumen; parenteral iron does not meet this mechanism.
What to do
No separation needed for parenteral iron dextran; if oral iron is used, separate from eltrombopag by 2 hours before or 4 hours after.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eltrombopag
- Alpelisib + Eltrombopag Moderate
- Aluminum hydroxide + Eltrombopag Moderate
- Amobarbital + Eltrombopag Moderate
- Artesunate + Eltrombopag Moderate
- Atazanavir + Eltrombopag Moderate
- Atorvastatin + Eltrombopag Moderate
Frequently asked questions
Can I take Eltrombopag with Iron dextran complex?
MediHelp rates the interaction as minor. Eltrombopag and Iron dextran complex have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Iron dextran is generally given parenterally, so little chelation of oral eltrombopag is expected. An interaction would only be plausible with oral iron products.
How serious is the interaction between Eltrombopag and Iron dextran complex?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No separation needed for parenteral iron dextran; if oral iron is used, separate from eltrombopag by 2 hours before or 4 hours after.
What other medicines interact with Eltrombopag?
MediHelp also lists interactions of Eltrombopag with, for example, Alpelisib, Aluminum hydroxide, Amobarbital. The full list is on the Eltrombopag page.
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