Drug reference
eltrombopag
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Miscellaneous (Miscellaneous)
Mechanism of action
Small-molecule thrombopoietin (TPO)-receptor agonist that interacts with human TPO receptor transmembrane domain of human TPO-receptor & initiates signaling cascades that induce proliferation & differentiation of megakaryocytes from bone marrow progenitor cells
Common side effects
- Upper respiratory tract infection
- Nasopharyngitis
- Anemia
- Headache
- Fatigue
- Nausea
- Pyrexia
Known interactions (13)
- aluminum hydroxide + eltrombopag Moderate
- calcium + eltrombopag Moderate
- calcium carbonate + eltrombopag Moderate
- carbonyl iron + eltrombopag Moderate
- eltrombopag + ferrous fumarate Moderate
- eltrombopag + ferrous gluconate Moderate
- eltrombopag + ferrous sulfate Moderate
- eltrombopag + iron Moderate
- eltrombopag + magnesium Moderate
- eltrombopag + magnesium citrate Moderate
- eltrombopag + magnesium hydroxide Moderate
- eltrombopag + magnesium sulphate Moderate
- eltrombopag + selenium Moderate
Related conditions
Frequently asked questions
What drug class is eltrombopag?
eltrombopag belongs to: Miscellaneous.
How does eltrombopag work?
Small-molecule thrombopoietin (TPO)-receptor agonist that interacts with human TPO receptor transmembrane domain of human TPO-receptor & initiates signaling cascades that induce proliferation & differentiation of megakaryocytes from bone marrow progenitor cells
What are the common side effects of eltrombopag?
Upper respiratory tract infection, Nasopharyngitis, Anemia, Headache, Fatigue, Nausea, Pyrexia
Which drugs interact with eltrombopag?
aluminum hydroxide, calcium, calcium carbonate, carbonyl iron, ferrous fumarate, ferrous gluconate, ferrous sulfate, iron, magnesium, magnesium citrate, magnesium hydroxide, magnesium sulphate, selenium
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