Drug interactions
Eltrombopag + Miconazole vaginal
Severity: Minor
Eltrombopag and Miconazole vaginal: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vaginal miconazole has low systemic absorption, so the effect on eltrombopag metabolism is likely negligible in most patients.
What this interaction means in plain words
Eltrombopag and Miconazole vaginal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Systemic miconazole inhibits CYP2C9, but vaginal exposure is typically too low to matter.
What to do
No action is routinely needed. Monitor liver tests per usual eltrombopag monitoring.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eltrombopag
- Alpelisib + Eltrombopag Moderate
- Aluminum hydroxide + Eltrombopag Moderate
- Amobarbital + Eltrombopag Moderate
- Artesunate + Eltrombopag Moderate
- Atazanavir + Eltrombopag Moderate
- Atorvastatin + Eltrombopag Moderate
Frequently asked questions
Can I take Eltrombopag with Miconazole vaginal?
MediHelp rates the interaction as minor. Eltrombopag and Miconazole vaginal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vaginal miconazole has low systemic absorption, so the effect on eltrombopag metabolism is likely negligible in most patients.
How serious is the interaction between Eltrombopag and Miconazole vaginal?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is routinely needed. Monitor liver tests per usual eltrombopag monitoring.
What other medicines interact with Eltrombopag?
MediHelp also lists interactions of Eltrombopag with, for example, Alpelisib, Aluminum hydroxide, Amobarbital. The full list is on the Eltrombopag page.
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