Drug interactions
Empagliflozin-metformin + Levonorgestrel
Severity: Minor
Empagliflozin-metformin and Levonorgestrel: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Progestins such as levonorgestrel may slightly impair glucose tolerance in some patients. The effect is usually small with low-dose or emergency contraceptive use.
What this interaction means in plain words
Empagliflozin-metformin and Levonorgestrel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Empagliflozin-metformin belongs to Endocrine; Levonorgestrel belongs to Endocrine.
Why it happens
Progestins may modestly reduce insulin sensitivity, opposing the effect of antidiabetic drugs.
What to do
Monitor blood glucose after starting levonorgestrel and adjust antidiabetic therapy only if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Empagliflozin-metformin
Other interactions of Levonorgestrel
Frequently asked questions
Can I take Empagliflozin-metformin with Levonorgestrel?
MediHelp rates the interaction as minor. Empagliflozin-metformin and Levonorgestrel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Progestins such as levonorgestrel may slightly impair glucose tolerance in some patients. The effect is usually small with low-dose or emergency contraceptive use.
How serious is the interaction between Empagliflozin-metformin and Levonorgestrel?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose after starting levonorgestrel and adjust antidiabetic therapy only if control worsens.
What other medicines interact with Empagliflozin-metformin?
MediHelp also lists interactions of Empagliflozin-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Empagliflozin-metformin page.
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