Drug interactions
Enalapril-hydrochlorothiazide + Triamcinolone acetonide injectable
Severity: Minor
Enalapril-hydrochlorothiazide and Triamcinolone acetonide injectable: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic corticosteroid exposure from injected triamcinolone may add to potassium loss from hydrochlorothiazide and can cause fluid retention that blunts antihypertensive effect. Triamcinolone has little mineralocorticoid activity so the effect is modest.
What this interaction means in plain words
Enalapril-hydrochlorothiazide and Triamcinolone acetonide injectable have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive renal potassium wasting and corticosteroid-related sodium and fluid retention opposing antihypertensive action.
What to do
Monitor serum potassium and blood pressure after injection, especially with repeated or large doses.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Enalapril-hydrochlorothiazide
- Aliskiren + Enalapril-hydrochlorothiazide Contraindicated
- Dofetilide + Enalapril-hydrochlorothiazide Contraindicated
- Enalapril-hydrochlorothiazide + Protein a column Contraindicated
- Enalapril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Amifostine + Enalapril-hydrochlorothiazide Major
- Amiloride + Enalapril-hydrochlorothiazide Major
Frequently asked questions
Can I take Enalapril-hydrochlorothiazide with Triamcinolone acetonide injectable?
MediHelp rates the interaction as minor. Enalapril-hydrochlorothiazide and Triamcinolone acetonide injectable have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic corticosteroid exposure from injected triamcinolone may add to potassium loss from hydrochlorothiazide and can cause fluid retention that blunts antihypertensive effect. Triamcinolone has little mineralocorticoid activity so the effect is modest.
How serious is the interaction between Enalapril-hydrochlorothiazide and Triamcinolone acetonide injectable?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and blood pressure after injection, especially with repeated or large doses.
What other medicines interact with Enalapril-hydrochlorothiazide?
MediHelp also lists interactions of Enalapril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Enalapril-hydrochlorothiazide page.
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