Drug interactions
Enoxaparin + Garlic
Severity: Moderate
Enoxaparin and Garlic: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Garlic supplements have antiplatelet properties and may add to bleeding risk with enoxaparin. Evidence consists mainly of case reports and pharmacodynamic data.
What this interaction means in plain words
Enoxaparin and Garlic can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Enoxaparin belongs to Cardiovascular; Garlic belongs to Gastrointestinal Tract.
Why it happens
Garlic constituents inhibit platelet aggregation, adding to enoxaparin's anticoagulant effect.
What to do
Advise avoiding concentrated garlic supplements during enoxaparin therapy. Monitor for bruising or bleeding if they are continued.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Enoxaparin
- Defibrotide + Enoxaparin Contraindicated
- Enoxaparin + Ketorolac Contraindicated
- Enoxaparin + Mifepristone Contraindicated
- Abciximab + Enoxaparin Major
- Aceclofenac + Enoxaparin Major
- Acetylsalicylic acid + Enoxaparin Major
Other interactions of Garlic
- Garlic + Saquinavir Major
- Aceclofenac + Garlic Moderate
- Acemetacin + Garlic Moderate
- Aescin + Garlic Moderate
- Alteplase + Garlic Moderate
- Argatroban + Garlic Moderate
Frequently asked questions
Can I take Enoxaparin with Garlic?
MediHelp rates the interaction as moderate. Enoxaparin and Garlic can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Garlic supplements have antiplatelet properties and may add to bleeding risk with enoxaparin. Evidence consists mainly of case reports and pharmacodynamic data.
How serious is the interaction between Enoxaparin and Garlic?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding concentrated garlic supplements during enoxaparin therapy. Monitor for bruising or bleeding if they are continued.
What other medicines interact with Enoxaparin?
MediHelp also lists interactions of Enoxaparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Enoxaparin page.
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