Drug interactions
Enoxaparin + Moexipril
Severity: Moderate
Enoxaparin and Moexipril: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Heparins can suppress aldosterone secretion and cause hyperkalemia. Combined with an ACE inhibitor, the risk of elevated potassium increases, especially in diabetes, renal impairment or prolonged use.
What this interaction means in plain words
Enoxaparin and Moexipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Enoxaparin belongs to Cardiovascular; Moexipril belongs to Cardiovascular.
Why it happens
Additive reduction in aldosterone effect: heparin inhibits adrenal aldosterone synthesis and ACE inhibition lowers angiotensin II.
What to do
Monitor serum potassium if combined for more than a few days, particularly in high-risk patients. Treat hyperkalemia or reconsider therapy if levels rise.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Moexipril
- Aliskiren + Moexipril Contraindicated
- Moexipril + Protein a column Contraindicated
- Moexipril + Sacubitril / valsartan Contraindicated
- Moexipril + Sacubitril-valsartan Contraindicated
- Amifostine + Moexipril Major
- Amiloride + Moexipril Major
Other interactions of Enoxaparin
- Defibrotide + Enoxaparin Contraindicated
- Enoxaparin + Ketorolac Contraindicated
- Enoxaparin + Mifepristone Contraindicated
- Abciximab + Enoxaparin Major
- Aceclofenac + Enoxaparin Major
- Acetylsalicylic acid + Enoxaparin Major
Frequently asked questions
Can I take Enoxaparin with Moexipril?
MediHelp rates the interaction as moderate. Enoxaparin and Moexipril can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Heparins can suppress aldosterone secretion and cause hyperkalemia. Combined with an ACE inhibitor, the risk of elevated potassium increases, especially in diabetes, renal impairment or prolonged use.
How serious is the interaction between Enoxaparin and Moexipril?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium if combined for more than a few days, particularly in high-risk patients. Treat hyperkalemia or reconsider therapy if levels rise.
What other medicines interact with Moexipril?
MediHelp also lists interactions of Moexipril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Moexipril page.
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