Drug interactions
Enoxaparin + Quinine
Severity: Moderate
Enoxaparin and Quinine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quinine can rarely cause thrombocytopenia and has been linked to bleeding disorders, which may add to the bleeding risk of low-molecular-weight heparin. The combination may raise the chance of hemorrhage, particularly in patients with other bleeding risk factors.
What this interaction means in plain words
Enoxaparin and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Enoxaparin belongs to Cardiovascular; Quinine belongs to Anti Parasitic.
Why it happens
Additive bleeding risk through quinine-associated thrombocytopenia and anticoagulation; no direct pharmacokinetic interaction is established.
What to do
Check baseline and periodic platelet counts and watch for bleeding signs during co-use. Stop quinine if platelets fall unexpectedly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Other interactions of Enoxaparin
- Defibrotide + Enoxaparin Contraindicated
- Enoxaparin + Ketorolac Contraindicated
- Enoxaparin + Mifepristone Contraindicated
- Abciximab + Enoxaparin Major
- Aceclofenac + Enoxaparin Major
- Acetylsalicylic acid + Enoxaparin Major
Frequently asked questions
Can I take Enoxaparin with Quinine?
MediHelp rates the interaction as moderate. Enoxaparin and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Quinine can rarely cause thrombocytopenia and has been linked to bleeding disorders, which may add to the bleeding risk of low-molecular-weight heparin. The combination may raise the chance of hemorrhage, particularly in patients with other bleeding risk factors.
How serious is the interaction between Enoxaparin and Quinine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline and periodic platelet counts and watch for bleeding signs during co-use. Stop quinine if platelets fall unexpectedly.
What other medicines interact with Quinine?
MediHelp also lists interactions of Quinine with, for example, Arsenic trioxide, Dofetilide, Dronedarone. The full list is on the Quinine page.
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