Drug interactions
Epinephrine + Formoterol-mometasone
Severity: Moderate
Epinephrine and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Epinephrine and formoterol are both adrenergic agonists, so combined use can produce excessive tachycardia, hypertension, arrhythmia and hypokalemia. Epinephrine for anaphylaxis should not be withheld because of formoterol.
What this interaction means in plain words
Epinephrine and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Epinephrine belongs to Endocrine; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive beta-adrenergic stimulation and hypokalemia.
What to do
Use epinephrine when clearly indicated, with ECG and potassium monitoring; avoid unnecessary additional sympathomimetics.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Epinephrine
- Epinephrine + Isocarboxazid Contraindicated
- Epinephrine + Phenelzine Contraindicated
- Epinephrine + Tranylcypromine Contraindicated
- Acebutolol + Epinephrine Major
- Amitriptyline + Epinephrine Major
- Amoxapine + Epinephrine Major
Frequently asked questions
Can I take Epinephrine with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Epinephrine and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Epinephrine and formoterol are both adrenergic agonists, so combined use can produce excessive tachycardia, hypertension, arrhythmia and hypokalemia. Epinephrine for anaphylaxis should not be withheld because of formoterol.
How serious is the interaction between Epinephrine and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use epinephrine when clearly indicated, with ECG and potassium monitoring; avoid unnecessary additional sympathomimetics.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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