Drug interactions
Epinephrine racemic + Formoterol-mometasone
Severity: Moderate
Epinephrine racemic and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Racemic epinephrine is a nonselective adrenergic agonist, so combining it with formoterol produces additive sympathomimetic effects. This may cause tachycardia, arrhythmia, hypertension and hypokalemia.
What this interaction means in plain words
Epinephrine racemic and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive adrenergic receptor stimulation, with beta-2 mediated hypokalemia and cardiac stimulation.
What to do
Avoid giving both unnecessarily. If both are needed, monitor heart rate, blood pressure, ECG and potassium, especially in patients with cardiovascular disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Frequently asked questions
Can I take Epinephrine racemic with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Epinephrine racemic and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Racemic epinephrine is a nonselective adrenergic agonist, so combining it with formoterol produces additive sympathomimetic effects. This may cause tachycardia, arrhythmia, hypertension and hypokalemia.
How serious is the interaction between Epinephrine racemic and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving both unnecessarily. If both are needed, monitor heart rate, blood pressure, ECG and potassium, especially in patients with cardiovascular disease.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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