Drug interactions
Epirubicin + Etrasimod
Severity: Major
Epirubicin and Etrasimod: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etrasimod lowers circulating lymphocytes, and epirubicin is myelosuppressive and immunosuppressive. Together they may produce additive immunosuppression and a higher risk of serious infection.
What this interaction means in plain words
Epirubicin and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Epirubicin belongs to Oncology; Etrasimod belongs to Gastrointestinal Tract.
Why it happens
Additive immunosuppression from lymphocyte sequestration by S1P receptor modulation and cytotoxic marrow suppression.
What to do
Avoid combining when possible, and allow time after stopping etrasimod. If used together, monitor blood counts and watch for infection.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Epirubicin and Etrasimod, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Epirubicin
- Adenovirus types 4 and 7 live + Epirubicin Contraindicated
- Belatacept + Epirubicin Major
- Cimetidine + Epirubicin Major
- Deferiprone + Epirubicin Major
- Dengue vaccine + Epirubicin Major
- Epirubicin + Fingolimod Major
Other interactions of Etrasimod
- Abatacept + Etrasimod Major
- Amiodarone + Etrasimod Major
- Anagrelide + Etrasimod Major
- Anakinra + Etrasimod Major
- Anti-thymocyte + Etrasimod Major
- Asenapine + Etrasimod Major
Frequently asked questions
Can I take Epirubicin with Etrasimod?
MediHelp rates the interaction as major. Epirubicin and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Etrasimod lowers circulating lymphocytes, and epirubicin is myelosuppressive and immunosuppressive. Together they may produce additive immunosuppression and a higher risk of serious infection.
How serious is the interaction between Epirubicin and Etrasimod?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining when possible, and allow time after stopping etrasimod. If used together, monitor blood counts and watch for infection.
What other medicines interact with Epirubicin?
MediHelp also lists interactions of Epirubicin with, for example, Adenovirus types 4 and 7 live, Belatacept, Cimetidine. The full list is on the Epirubicin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
