Drug interactions
Eprosartan + Insulin degludec-liraglutide
Severity: Minor
Eprosartan and Insulin degludec-liraglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin II receptor blockers may modestly improve insulin sensitivity, which can add to the glucose-lowering effect of insulin degludec and liraglutide. Hypoglycemia is uncommon but possible, especially when treatment is started.
What this interaction means in plain words
Eprosartan and Insulin degludec-liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Eprosartan belongs to Cardiovascular; Insulin degludec-liraglutide belongs to Endocrine.
Why it happens
Possible improvement in insulin sensitivity by angiotensin II receptor blockade, producing an additive pharmacodynamic glucose-lowering effect.
What to do
Monitor blood glucose when eprosartan is started or stopped. Reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-liraglutide
Other interactions of Eprosartan
- Aliskiren + Eprosartan Contraindicated
- Eprosartan + Sparsentan Contraindicated
- Amifostine + Eprosartan Major
- Amiloride + Eprosartan Major
- Amlodipine-benazepril + Eprosartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Eprosartan Major
Frequently asked questions
Can I take Eprosartan with Insulin degludec-liraglutide?
MediHelp rates the interaction as minor. Eprosartan and Insulin degludec-liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Angiotensin II receptor blockers may modestly improve insulin sensitivity, which can add to the glucose-lowering effect of insulin degludec and liraglutide. Hypoglycemia is uncommon but possible, especially when treatment is started.
How serious is the interaction between Eprosartan and Insulin degludec-liraglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when eprosartan is started or stopped. Reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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