Drug interactions
Eprosartan-hydrochlorothiazide + Minoxidil
Severity: Moderate
Eprosartan-hydrochlorothiazide and Minoxidil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Minoxidil is a potent vasodilator and combined use with a thiazide and an angiotensin receptor blocker lowers blood pressure further. Thiazides are often used with minoxidil to counter fluid retention, but excessive hypotension can occur.
What this interaction means in plain words
Eprosartan-hydrochlorothiazide and Minoxidil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Eprosartan-hydrochlorothiazide belongs to Cardiovascular; Minoxidil belongs to Cardiovascular.
Why it happens
Additive blood pressure lowering through vasodilation, diuresis and angiotensin receptor blockade.
What to do
Monitor blood pressure, heart rate and fluid status, and titrate doses gradually. Watch for hypotension, especially after dose changes.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Eprosartan-hydrochlorothiazide and Minoxidil, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Other interactions of Minoxidil
Frequently asked questions
Can I take Eprosartan-hydrochlorothiazide with Minoxidil?
MediHelp rates the interaction as moderate. Eprosartan-hydrochlorothiazide and Minoxidil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Minoxidil is a potent vasodilator and combined use with a thiazide and an angiotensin receptor blocker lowers blood pressure further. Thiazides are often used with minoxidil to counter fluid retention, but excessive hypotension can occur.
How serious is the interaction between Eprosartan-hydrochlorothiazide and Minoxidil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and fluid status, and titrate doses gradually. Watch for hypotension, especially after dose changes.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
