Drug interactions
Ergoloid mesylates + Quetiapine
Severity: Minor
Ergoloid mesylates and Quetiapine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ergoloid mesylates have dopaminergic and serotonergic activity that may oppose dopamine blockade by quetiapine. Serotonin syndrome or neuroleptic malignant syndrome is theoretical, and documented cases are lacking.
What this interaction means in plain words
Ergoloid mesylates and Quetiapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical opposing dopaminergic and serotonergic receptor effects; mechanism not firmly established.
What to do
Monitor for mental status changes, rigidity, hyperthermia and autonomic instability when starting or adjusting either drug.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quetiapine
- Adagrasib + Quetiapine Major
- Amiodarone + Quetiapine Major
- Amisulpride + Quetiapine Major
- Amoxapine + Quetiapine Major
- Anagrelide + Quetiapine Major
- Apalutamide + Quetiapine Major
Frequently asked questions
Can I take Ergoloid mesylates with Quetiapine?
MediHelp rates the interaction as minor. Ergoloid mesylates and Quetiapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ergoloid mesylates have dopaminergic and serotonergic activity that may oppose dopamine blockade by quetiapine. Serotonin syndrome or neuroleptic malignant syndrome is theoretical, and documented cases are lacking.
How serious is the interaction between Ergoloid mesylates and Quetiapine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for mental status changes, rigidity, hyperthermia and autonomic instability when starting or adjusting either drug.
What other medicines interact with Quetiapine?
MediHelp also lists interactions of Quetiapine with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Quetiapine page.
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