Drug interactions
Eribulin + Etrasimod
Severity: Moderate
Eribulin and Etrasimod: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eribulin is a myelosuppressive cytotoxic, and etrasimod lowers circulating lymphocytes by sequestering them in lymphoid tissue. Together they may deepen immunosuppression and increase the risk of infection.
What this interaction means in plain words
Eribulin and Etrasimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Eribulin belongs to Oncology; Etrasimod belongs to Gastrointestinal Tract.
Why it happens
Additive immunosuppression from eribulin myelosuppression and etrasimod S1P receptor modulation with lymphocyte sequestration.
What to do
Monitor blood counts and watch closely for infection. Consider whether etrasimod should be held during chemotherapy, as its effects on lymphocytes persist after stopping.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Eribulin
Other interactions of Etrasimod
- Abatacept + Etrasimod Major
- Amiodarone + Etrasimod Major
- Anagrelide + Etrasimod Major
- Anakinra + Etrasimod Major
- Anti-thymocyte + Etrasimod Major
- Asenapine + Etrasimod Major
Frequently asked questions
Can I take Eribulin with Etrasimod?
MediHelp rates the interaction as moderate. Eribulin and Etrasimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eribulin is a myelosuppressive cytotoxic, and etrasimod lowers circulating lymphocytes by sequestering them in lymphoid tissue. Together they may deepen immunosuppression and increase the risk of infection.
How serious is the interaction between Eribulin and Etrasimod?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts and watch closely for infection. Consider whether etrasimod should be held during chemotherapy, as its effects on lymphocytes persist after stopping.
What other medicines interact with Eribulin?
MediHelp also lists interactions of Eribulin with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Eribulin page.
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