Drug interactions
Eribulin + Isoflurane
Severity: Moderate
Eribulin and Isoflurane: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eribulin can prolong the QT interval and isoflurane may add to this effect. The risk is greatest with electrolyte abnormalities or bradycardia.
What this interaction means in plain words
Eribulin and Isoflurane can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Eribulin belongs to Oncology; Isoflurane belongs to Central Nervous System.
Why it happens
Additive QT prolongation.
What to do
Check electrolytes and baseline QTc before anesthesia and monitor the ECG during surgery.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Isoflurane
Other interactions of Eribulin
Frequently asked questions
Can I take Eribulin with Isoflurane?
MediHelp rates the interaction as moderate. Eribulin and Isoflurane can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eribulin can prolong the QT interval and isoflurane may add to this effect. The risk is greatest with electrolyte abnormalities or bradycardia.
How serious is the interaction between Eribulin and Isoflurane?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check electrolytes and baseline QTc before anesthesia and monitor the ECG during surgery.
What other medicines interact with Isoflurane?
MediHelp also lists interactions of Isoflurane with, for example, Adrenaline-articaine, Amisulpride, Arsenic trioxide. The full list is on the Isoflurane page.
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