Drug interactions
Eribulin + Salbutamol
Severity: Moderate
Eribulin and Salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs have been associated with QT interval prolongation, so combined use may add to the risk of ventricular arrhythmia. The risk is higher in patients with electrolyte disturbances or existing cardiac disease.
What this interaction means in plain words
Eribulin and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Eribulin belongs to Oncology; Salbutamol belongs to Respiratory.
Why it happens
Additive pharmacodynamic QT prolongation, with beta-2 agonist-induced hypokalemia possibly contributing.
What to do
Check baseline ECG, potassium and magnesium and correct deficits before starting. Monitor ECG during treatment, especially with high-dose or repeated salbutamol.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Salbutamol
Other interactions of Eribulin
Frequently asked questions
Can I take Eribulin with Salbutamol?
MediHelp rates the interaction as moderate. Eribulin and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have been associated with QT interval prolongation, so combined use may add to the risk of ventricular arrhythmia. The risk is higher in patients with electrolyte disturbances or existing cardiac disease.
How serious is the interaction between Eribulin and Salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG, potassium and magnesium and correct deficits before starting. Monitor ECG during treatment, especially with high-dose or repeated salbutamol.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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