Drug interactions
Erythromycin + Oxcarbazepine
Severity: Minor
Erythromycin and Oxcarbazepine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxcarbazepine is a weak inducer of CYP3A4 and may modestly lower erythromycin exposure. This could reduce antibacterial effectiveness, although the effect is generally small.
What this interaction means in plain words
Erythromycin and Oxcarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Erythromycin belongs to Anti Bacterial; Oxcarbazepine belongs to Central Nervous System.
Why it happens
Weak induction of CYP3A4 by oxcarbazepine may increase erythromycin metabolism.
What to do
No routine change is needed; monitor clinical response to the antibiotic and consider an alternative if treatment fails.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Erythromycin
- Conivaptan + Erythromycin Contraindicated
- Dihydroergotamine intranasal + Erythromycin Contraindicated
- Dihydroergotamine + Erythromycin Contraindicated
- Domperidone + Erythromycin Contraindicated
- Dronedarone + Erythromycin Contraindicated
- Droperidol + Erythromycin Contraindicated
Other interactions of Oxcarbazepine
- Cabotegravir + Oxcarbazepine Contraindicated
- Oxcarbazepine + Rilpivirine Contraindicated
- Artemether / lumefantrine + Oxcarbazepine Major
- Atazanavir + Oxcarbazepine Major
- Benzhydrocodone / acetaminophen + Oxcarbazepine Major
- Bictegravir + Oxcarbazepine Major
Frequently asked questions
Can I take Erythromycin with Oxcarbazepine?
MediHelp rates the interaction as minor. Erythromycin and Oxcarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oxcarbazepine is a weak inducer of CYP3A4 and may modestly lower erythromycin exposure. This could reduce antibacterial effectiveness, although the effect is generally small.
How serious is the interaction between Erythromycin and Oxcarbazepine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor clinical response to the antibiotic and consider an alternative if treatment fails.
What other medicines interact with Erythromycin?
MediHelp also lists interactions of Erythromycin with, for example, Conivaptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Erythromycin page.
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