Drug interactions
Erythromycin + Telavancin
Severity: Moderate
Erythromycin and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Telavancin can prolong the QTc interval, and erythromycin has the same effect. Together they may raise the risk of arrhythmia, particularly in patients with cardiac disease or electrolyte abnormalities.
What this interaction means in plain words
Erythromycin and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Erythromycin belongs to Anti Bacterial; Telavancin belongs to Anti Bacterial.
Why it happens
Additive QT prolongation.
What to do
Monitor ECG and electrolytes; avoid or choose alternatives in patients with congenital long QT or uncompensated heart failure.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Erythromycin
- Conivaptan + Erythromycin Contraindicated
- Dihydroergotamine intranasal + Erythromycin Contraindicated
- Dihydroergotamine + Erythromycin Contraindicated
- Domperidone + Erythromycin Contraindicated
- Dronedarone + Erythromycin Contraindicated
- Droperidol + Erythromycin Contraindicated
Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Frequently asked questions
Can I take Erythromycin with Telavancin?
MediHelp rates the interaction as moderate. Erythromycin and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Telavancin can prolong the QTc interval, and erythromycin has the same effect. Together they may raise the risk of arrhythmia, particularly in patients with cardiac disease or electrolyte abnormalities.
How serious is the interaction between Erythromycin and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes; avoid or choose alternatives in patients with congenital long QT or uncompensated heart failure.
What other medicines interact with Erythromycin?
MediHelp also lists interactions of Erythromycin with, for example, Conivaptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Erythromycin page.
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