Drug interactions
Erythromycin base + Formoterol-mometasone
Severity: Moderate
Erythromycin base and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Erythromycin can prolong the QT interval and formoterol may add to this effect and lower potassium. The combination may modestly raise the risk of ventricular arrhythmia, particularly in patients with other risk factors.
What this interaction means in plain words
Erythromycin base and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation, with beta-2 agonist induced hypokalemia contributing.
What to do
Check for other QT risk factors and correct potassium and magnesium. Consider an alternative antibiotic such as azithromycin with a lower risk profile in at-risk patients, or monitor ECG.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Frequently asked questions
Can I take Erythromycin base with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Erythromycin base and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Erythromycin can prolong the QT interval and formoterol may add to this effect and lower potassium. The combination may modestly raise the risk of ventricular arrhythmia, particularly in patients with other risk factors.
How serious is the interaction between Erythromycin base and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check for other QT risk factors and correct potassium and magnesium. Consider an alternative antibiotic such as azithromycin with a lower risk profile in at-risk patients, or monitor ECG.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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