Drug interactions
Escitalopram + Fluticasone-vilanterol
Severity: Moderate
Escitalopram and Fluticasone-vilanterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Escitalopram causes dose-dependent QT prolongation, and vilanterol can add cardiovascular stimulation and potassium lowering. The combined risk of arrhythmia is small in most patients but higher with other risk factors.
What this interaction means in plain words
Escitalopram and Fluticasone-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Escitalopram belongs to Central Nervous System; Fluticasone-vilanterol belongs to Respiratory.
Why it happens
Additive QTc prolongation and beta-agonist-related hypokalemia.
What to do
Keep escitalopram at the lowest effective dose and check ECG and potassium in patients with cardiac risk factors. Report palpitations or syncope promptly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fluticasone-vilanterol
Other interactions of Escitalopram
- Cisapride + Escitalopram Contraindicated
- Citalopram + Escitalopram Contraindicated
- Escitalopram + Isocarboxazid Contraindicated
- Escitalopram + Methylene blue Contraindicated
- Escitalopram + Phenelzine Contraindicated
- Escitalopram + Pimozide Contraindicated
Frequently asked questions
Can I take Escitalopram with Fluticasone-vilanterol?
MediHelp rates the interaction as moderate. Escitalopram and Fluticasone-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Escitalopram causes dose-dependent QT prolongation, and vilanterol can add cardiovascular stimulation and potassium lowering. The combined risk of arrhythmia is small in most patients but higher with other risk factors.
How serious is the interaction between Escitalopram and Fluticasone-vilanterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Keep escitalopram at the lowest effective dose and check ECG and potassium in patients with cardiac risk factors. Report palpitations or syncope promptly.
What other medicines interact with Fluticasone-vilanterol?
MediHelp also lists interactions of Fluticasone-vilanterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Fluticasone-vilanterol page.
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