Drug interactions
Escitalopram + Nebivolol
Severity: Minor
Escitalopram and Nebivolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nebivolol is metabolised mainly by CYP2D6, which escitalopram inhibits weakly. Nebivolol exposure may rise slightly, which would enhance beta-blockade, though this is rarely clinically important.
What this interaction means in plain words
Escitalopram and Nebivolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Escitalopram belongs to Central Nervous System; Nebivolol belongs to Cardiovascular.
Why it happens
Weak CYP2D6 inhibition by escitalopram reduces the metabolism of nebivolol.
What to do
No routine adjustment is needed. Check heart rate and blood pressure if bradycardia or dizziness develops after starting escitalopram.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Other interactions of Escitalopram
- Cisapride + Escitalopram Contraindicated
- Citalopram + Escitalopram Contraindicated
- Escitalopram + Isocarboxazid Contraindicated
- Escitalopram + Methylene blue Contraindicated
- Escitalopram + Phenelzine Contraindicated
- Escitalopram + Pimozide Contraindicated
Frequently asked questions
Can I take Escitalopram with Nebivolol?
MediHelp rates the interaction as minor. Escitalopram and Nebivolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nebivolol is metabolised mainly by CYP2D6, which escitalopram inhibits weakly. Nebivolol exposure may rise slightly, which would enhance beta-blockade, though this is rarely clinically important.
How serious is the interaction between Escitalopram and Nebivolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Check heart rate and blood pressure if bradycardia or dizziness develops after starting escitalopram.
What other medicines interact with Nebivolol?
MediHelp also lists interactions of Nebivolol with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Nebivolol page.
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