Drug interactions
Ethanol + Quetiapine
Severity: Moderate
Ethanol and Quetiapine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Alcohol adds to quetiapine's sedation, impairs cognition and coordination, and may worsen orthostatic hypotension. Heavy intake can increase the risk of falls and respiratory depression.
What this interaction means in plain words
Ethanol and Quetiapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depression.
What to do
Advise patients to avoid alcohol during quetiapine therapy. Counsel on driving and operating machinery risk if alcohol is consumed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quetiapine
- Adagrasib + Quetiapine Major
- Amiodarone + Quetiapine Major
- Amisulpride + Quetiapine Major
- Amoxapine + Quetiapine Major
- Anagrelide + Quetiapine Major
- Apalutamide + Quetiapine Major
Frequently asked questions
Can I take Ethanol with Quetiapine?
MediHelp rates the interaction as moderate. Ethanol and Quetiapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Alcohol adds to quetiapine's sedation, impairs cognition and coordination, and may worsen orthostatic hypotension. Heavy intake can increase the risk of falls and respiratory depression.
How serious is the interaction between Ethanol and Quetiapine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid alcohol during quetiapine therapy. Counsel on driving and operating machinery risk if alcohol is consumed.
What other medicines interact with Quetiapine?
MediHelp also lists interactions of Quetiapine with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Quetiapine page.
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