Drug interactions
Ethanol + Ramelteon
Severity: Moderate
Ethanol and Ramelteon: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Alcohol depresses the CNS and may worsen drowsiness and psychomotor impairment when taken with ramelteon. Alcohol may also reduce the benefit of insomnia treatment.
What this interaction means in plain words
Ethanol and Ramelteon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depressant effects.
What to do
Advise patients to avoid alcohol while taking ramelteon, especially near bedtime. Counsel against driving after combined use.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ramelteon
- Calcium / magnesium / potassium / sodium oxybates + Ramelteon Contraindicated
- Fluvoxamine + Ramelteon Contraindicated
- Ramelteon + Sodium oxybate Contraindicated
- Alfentanil + Ramelteon Moderate
- Amitriptyline + Ramelteon Moderate
- Amobarbital + Ramelteon Moderate
Frequently asked questions
Can I take Ethanol with Ramelteon?
MediHelp rates the interaction as moderate. Ethanol and Ramelteon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Alcohol depresses the CNS and may worsen drowsiness and psychomotor impairment when taken with ramelteon. Alcohol may also reduce the benefit of insomnia treatment.
How serious is the interaction between Ethanol and Ramelteon?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid alcohol while taking ramelteon, especially near bedtime. Counsel against driving after combined use.
What other medicines interact with Ramelteon?
MediHelp also lists interactions of Ramelteon with, for example, Calcium / magnesium / potassium / sodium oxybates, Fluvoxamine, Sodium oxybate. The full list is on the Ramelteon page.
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