Drug interactions
Etodolac + Reishi
Severity: Minor
Etodolac and Reishi: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Reishi mushroom has reported antiplatelet activity and may add to the bleeding tendency caused by NSAIDs. Clinical data are limited.
What this interaction means in plain words
Etodolac and Reishi have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive inhibition of platelet aggregation by reishi constituents together with NSAID COX-1 inhibition; the mechanism is not firmly established.
What to do
Ask patients about herbal use and advise them to report bruising or bleeding. Consider avoiding reishi in those with other bleeding risks.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Etodolac
- Etodolac + Ketorolac Contraindicated
- Etodolac + Ketorolac intranasal Contraindicated
- Aceclofenac + Etodolac Major
- Acemetacin + Etodolac Major
- Acetylsalicylic acid + Etodolac Major
- Alteplase + Etodolac Major
Frequently asked questions
Can I take Etodolac with Reishi?
MediHelp rates the interaction as minor. Etodolac and Reishi have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reishi mushroom has reported antiplatelet activity and may add to the bleeding tendency caused by NSAIDs. Clinical data are limited.
How serious is the interaction between Etodolac and Reishi?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and advise them to report bruising or bleeding. Consider avoiding reishi in those with other bleeding risks.
What other medicines interact with Etodolac?
MediHelp also lists interactions of Etodolac with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Etodolac page.
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