Drug interactions
Etrasimod + Nifedipine
Severity: Minor
Etrasimod and Nifedipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etrasimod can transiently slow heart rate and AV conduction when started. Nifedipine, a dihydropyridine, has little direct nodal effect, so significant additive bradycardia is not expected, but hypotension may add.
What this interaction means in plain words
Etrasimod and Nifedipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Etrasimod belongs to Gastrointestinal Tract; Nifedipine belongs to Cardiovascular.
Why it happens
Possible additive hemodynamic effects; dihydropyridines do not strongly depress AV conduction.
What to do
Monitor heart rate and blood pressure during etrasimod initiation in patients on nifedipine.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nifedipine
Other interactions of Etrasimod
- Abatacept + Etrasimod Major
- Amiodarone + Etrasimod Major
- Anagrelide + Etrasimod Major
- Anakinra + Etrasimod Major
- Anti-thymocyte + Etrasimod Major
- Asenapine + Etrasimod Major
Frequently asked questions
Can I take Etrasimod with Nifedipine?
MediHelp rates the interaction as minor. Etrasimod and Nifedipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Etrasimod can transiently slow heart rate and AV conduction when started. Nifedipine, a dihydropyridine, has little direct nodal effect, so significant additive bradycardia is not expected, but hypotension may add.
How serious is the interaction between Etrasimod and Nifedipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure during etrasimod initiation in patients on nifedipine.
What other medicines interact with Nifedipine?
MediHelp also lists interactions of Nifedipine with, for example, Amifostine, Amlodipine-benazepril, Apalutamide. The full list is on the Nifedipine page.
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