Drug interactions
Felodipine + Magnesium supplement
Severity: Moderate
Felodipine and Magnesium supplement: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Magnesium has vasodilating and calcium-antagonist properties and may add to the blood pressure lowering of felodipine. Rarely, neuromuscular weakness or marked hypotension has been described with parenteral magnesium and calcium channel blockers.
What this interaction means in plain words
Felodipine and Magnesium supplement can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive calcium antagonism and vasodilation.
What to do
Monitor blood pressure, particularly with intravenous magnesium, and watch for muscle weakness.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Frequently asked questions
Can I take Felodipine with Magnesium supplement?
MediHelp rates the interaction as moderate. Felodipine and Magnesium supplement can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium has vasodilating and calcium-antagonist properties and may add to the blood pressure lowering of felodipine. Rarely, neuromuscular weakness or marked hypotension has been described with parenteral magnesium and calcium channel blockers.
How serious is the interaction between Felodipine and Magnesium supplement?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, particularly with intravenous magnesium, and watch for muscle weakness.
What other medicines interact with Felodipine?
MediHelp also lists interactions of Felodipine with, for example, Itraconazole, Aldesleukin, Amifostine. The full list is on the Felodipine page.
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