Drug interactions
Felodipine + Metformin
Severity: Minor
Felodipine and Metformin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium channel blockers can modestly worsen glycemic control in some patients. The effect is generally small and clinically minor.
What this interaction means in plain words
Felodipine and Metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Felodipine belongs to Cardiovascular; Metformin belongs to Endocrine.
Why it happens
Calcium channel blockade may slightly reduce insulin secretion or sensitivity; mechanism not well established.
What to do
Monitor blood glucose when felodipine is started or stopped and adjust metformin if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Other interactions of Metformin
Frequently asked questions
Can I take Felodipine with Metformin?
MediHelp rates the interaction as minor. Felodipine and Metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium channel blockers can modestly worsen glycemic control in some patients. The effect is generally small and clinically minor.
How serious is the interaction between Felodipine and Metformin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when felodipine is started or stopped and adjust metformin if needed.
What other medicines interact with Felodipine?
MediHelp also lists interactions of Felodipine with, for example, Itraconazole, Aldesleukin, Amifostine. The full list is on the Felodipine page.
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