Drug interactions
Felodipine + Trimagnesium
Severity: Minor
Felodipine and Trimagnesium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Magnesium has calcium-antagonistic properties and may add to the vasodilating effect of calcium channel blockers. This can potentially cause hypotension or neuromuscular weakness, mainly with parenteral or high-dose magnesium.
What this interaction means in plain words
Felodipine and Trimagnesium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive pharmacodynamic reduction of calcium-dependent vascular smooth muscle and neuromuscular function.
What to do
Oral magnesium supplements rarely need action; monitor blood pressure if high doses are used. With intravenous magnesium, monitor blood pressure and neuromuscular status.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Frequently asked questions
Can I take Felodipine with Trimagnesium?
MediHelp rates the interaction as minor. Felodipine and Trimagnesium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Magnesium has calcium-antagonistic properties and may add to the vasodilating effect of calcium channel blockers. This can potentially cause hypotension or neuromuscular weakness, mainly with parenteral or high-dose magnesium.
How serious is the interaction between Felodipine and Trimagnesium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Oral magnesium supplements rarely need action; monitor blood pressure if high doses are used. With intravenous magnesium, monitor blood pressure and neuromuscular status.
What other medicines interact with Felodipine?
MediHelp also lists interactions of Felodipine with, for example, Itraconazole, Aldesleukin, Amifostine. The full list is on the Felodipine page.
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