Drug interactions
Ferrous fumarate + Sarecycline
Severity: Moderate
Ferrous fumarate and Sarecycline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral iron can bind sarecycline in the gut and reduce its absorption. Lower exposure may weaken acne treatment response, although sarecycline is less affected than older tetracyclines.
What this interaction means in plain words
Ferrous fumarate and Sarecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ferrous fumarate belongs to Miscellaneous; Sarecycline belongs to Anti Bacterial.
Why it happens
Chelation of sarecycline by iron cations in the gastrointestinal tract reduces absorption.
What to do
Separate sarecycline and oral iron by at least 2 to 3 hours, taking sarecycline first where possible. Reassess acne response if iron cannot be separated.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ferrous fumarate
Other interactions of Sarecycline
- Acitretin + Sarecycline Contraindicated
- Isotretinoin + Sarecycline Major
- Sarecycline + Tretinoin Major
- Aluminum hydroxide + Sarecycline Moderate
- Calcium carbonate + Sarecycline Moderate
- Calcium + Sarecycline Moderate
Frequently asked questions
Can I take Ferrous fumarate with Sarecycline?
MediHelp rates the interaction as moderate. Ferrous fumarate and Sarecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron can bind sarecycline in the gut and reduce its absorption. Lower exposure may weaken acne treatment response, although sarecycline is less affected than older tetracyclines.
How serious is the interaction between Ferrous fumarate and Sarecycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate sarecycline and oral iron by at least 2 to 3 hours, taking sarecycline first where possible. Reassess acne response if iron cannot be separated.
What other medicines interact with Ferrous fumarate?
MediHelp also lists interactions of Ferrous fumarate with, for example, Ciprofloxacin, Acetohydroxamic acid, Aluminum hydroxide. The full list is on the Ferrous fumarate page.
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