Drug interactions
Ferrous sulfate + Nizatidine
Severity: Moderate
Ferrous sulfate and Nizatidine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Reduced gastric acid lowers solubilization and absorption of oral ferrous iron. Long-term co-use may reduce the response to iron replacement.
What this interaction means in plain words
Ferrous sulfate and Nizatidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ferrous sulfate belongs to Miscellaneous; Nizatidine belongs to Gastrointestinal Tract.
Why it happens
Nizatidine increases gastric pH and impairs iron dissolution and absorption.
What to do
Monitor hemoglobin and ferritin during prolonged co-therapy. Consider taking iron with vitamin C or reassess the need for the acid suppressant.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nizatidine
- Atazanavir + Nizatidine Major
- Dasatinib + Nizatidine Major
- Erlotinib + Nizatidine Major
- Itraconazole + Nizatidine Major
- Ketoconazole + Nizatidine Major
- Nizatidine + Pazopanib Major
Other interactions of Ferrous sulfate
Frequently asked questions
Can I take Ferrous sulfate with Nizatidine?
MediHelp rates the interaction as moderate. Ferrous sulfate and Nizatidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Reduced gastric acid lowers solubilization and absorption of oral ferrous iron. Long-term co-use may reduce the response to iron replacement.
How serious is the interaction between Ferrous sulfate and Nizatidine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor hemoglobin and ferritin during prolonged co-therapy. Consider taking iron with vitamin C or reassess the need for the acid suppressant.
What other medicines interact with Nizatidine?
MediHelp also lists interactions of Nizatidine with, for example, Atazanavir, Dasatinib, Erlotinib. The full list is on the Nizatidine page.
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