Drug interactions
Ferrous sulfate + Sarecycline
Severity: Minor
Ferrous sulfate and Sarecycline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iron may bind oral sarecycline in the gut, but sarecycline's absorption is less affected by cations than older tetracyclines. Reduced effect on acne or infection control is possible.
What this interaction means in plain words
Ferrous sulfate and Sarecycline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ferrous sulfate belongs to Miscellaneous; Sarecycline belongs to Anti Bacterial.
Why it happens
Chelation of sarecycline by iron cations in the gastrointestinal tract may reduce absorption.
What to do
Separate sarecycline and iron doses by at least 2 to 3 hours as a precaution.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ferrous sulfate
Other interactions of Sarecycline
- Acitretin + Sarecycline Contraindicated
- Isotretinoin + Sarecycline Major
- Sarecycline + Tretinoin Major
- Aluminum hydroxide + Sarecycline Moderate
- Calcium carbonate + Sarecycline Moderate
- Calcium + Sarecycline Moderate
Frequently asked questions
Can I take Ferrous sulfate with Sarecycline?
MediHelp rates the interaction as minor. Ferrous sulfate and Sarecycline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Iron may bind oral sarecycline in the gut, but sarecycline's absorption is less affected by cations than older tetracyclines. Reduced effect on acne or infection control is possible.
How serious is the interaction between Ferrous sulfate and Sarecycline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate sarecycline and iron doses by at least 2 to 3 hours as a precaution.
What other medicines interact with Ferrous sulfate?
MediHelp also lists interactions of Ferrous sulfate with, for example, Ciprofloxacin, Dimercaprol, Acetohydroxamic acid. The full list is on the Ferrous sulfate page.
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