Drug interactions
Ferrous sulfate + Vitamin e
Severity: Minor
Ferrous sulfate and Vitamin e: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
High-dose vitamin E may blunt the hematologic response to iron in iron-deficient patients according to limited reports. The clinical effect is generally small.
What this interaction means in plain words
Ferrous sulfate and Vitamin e have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ferrous sulfate belongs to Miscellaneous; Vitamin e belongs to Gastrointestinal Tract.
Why it happens
The mechanism is not well established; possible reduced iron absorption or antioxidant interference with iron.
What to do
Separate the doses by a few hours and monitor hemoglobin and ferritin if high-dose vitamin E is used long term.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ferrous sulfate
Other interactions of Vitamin e
- Betrixaban + Vitamin e Moderate
- Phenindione + Vitamin e Moderate
- Selumetinib + Vitamin e Moderate
- Vitamin e + Warfarin Moderate
- Alfalfa + Vitamin e Minor
- Antithrombin alfa + Vitamin e Minor
Frequently asked questions
Can I take Ferrous sulfate with Vitamin e?
MediHelp rates the interaction as minor. Ferrous sulfate and Vitamin e have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. High-dose vitamin E may blunt the hematologic response to iron in iron-deficient patients according to limited reports. The clinical effect is generally small.
How serious is the interaction between Ferrous sulfate and Vitamin e?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate the doses by a few hours and monitor hemoglobin and ferritin if high-dose vitamin E is used long term.
What other medicines interact with Ferrous sulfate?
MediHelp also lists interactions of Ferrous sulfate with, for example, Ciprofloxacin, Dimercaprol, Acetohydroxamic acid. The full list is on the Ferrous sulfate page.
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